In this pilot study, we investigated one of the most common forms of cue competition, namely the overshadowing effect, between visual landmarks during spatial learning in mice. 4CHU Caen, Clinical Research Department, CHU Caen Côte de Nacre, UNICAEN, Caen, FranceĪnimals use distal and proximal visual cues to accurately navigate in their environment, with the possibility of the occurrence of associative mechanisms such as cue competition as previously reported in honey-bees, rats, birds and humans.3Department of Mathematics, University of Bergen, Bergen, Norway.2Center for Mind/Brain Sciences, University of Trento, Rovereto, Italy.1Normandie Université, UNICAEN, INSERM, Physiopathology and Imaging of Neurological Disorders, Caen, France.Marie Hébert 1,2 Jan Bulla 3 Denis Vivien 1,4† Véronique Agin 1*†